A targeted fungal prophylaxis protocol with static dosed fluconazole significantly reduces invasive fungal infection after liver transplantation.

Margaret R JorgensonJillian L DescourouezNicholas A MarkaGlen E LeversonJeannina A SmithDavid R AndesLuis A FernandezDavid P Foley

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2019)

Implementation of a targeted FPP utilizing static dosing of fluconazole 400 mg × 14 days to those that meet high-risk criteria significantly reduces invasive fungal infection after liver transplant. Use of this protocol did not adversely affect fungal epidemiology and may have a positive impact on allograft and patient survival. Future large prospective studies are needed to better evaluate survival impact.

Keyphrases

randomized controlled trial
candida albicans
cell wall
cancer therapy
healthcare
primary care
risk factors
current status
quality improvement