Cytokeratin 19 fragment is associated with severity and poor prognosis of interstitial lung disease in anti-MDA5 antibody-positive dermatomyositis.
Xianhua GuiMiao MaJingjing DingShenYun ShiXiaoyan XinXiaohua QiuYingwei ZhangYuying QiuMin CaoMei HuangMengshu CaoJinghong DaiHourong CaiYonglong XiaoPublished in: Rheumatology (Oxford, England) (2021)
CYFRA21-1 could be a useful serum indicator associated with occurrence of A/SIP in MDA5-DM-ILD. Moreover, it was associated with a poor survival in MDA5-DM-ILD patients.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- poor prognosis
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- breast cancer cells
- end stage renal disease
- long non coding rna
- ejection fraction
- chronic kidney disease
- newly diagnosed
- risk assessment
- peritoneal dialysis
- cell cycle arrest
- prognostic factors
- type diabetes
- disease activity
- insulin resistance
- skeletal muscle