Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis.

Wenhua HePeng ChenYupeng LeiLiang XiaPi LiuYong ZhuHao ZengYao WuHuajing KeXin HuangWenhao CaiXin SunWei HuangRobert SuttonYin ZhuNong Hua Lu

Published in: Critical care (London, England) (2022)

Neostigmine reduced IAP and promoted defecation in patients with AP and IAH. These results warrant a larger, placebo-controlled, double-blind phase III trial. Trial registration Clinical Trial No: NCT02543658 (registered August /27, 2015).

Keyphrases

phase iii
placebo controlled
double blind
clinical trial
study protocol
phase ii
randomized controlled trial
open label
blood pressure
phase ii study
transcription factor
locally advanced
arterial hypertension