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ctDNA Monitoring for Small Cell Lung Cancer: Ready for Prime Time?

Bruna PelliniAadel A Chaudhuri
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Small cell lung cancer (SCLC) is the deadliest form of lung cancer and has few precision medicine approaches available. A recent study analyzed circulating tumor DNA (ctDNA) in 33 patients with extensive-stage SCLC and showed that ctDNA levels and response patterns correlate strongly with clinical response and survival outcomes. See related article by Sivapalan et al., p. xxxx.
Keyphrases
  • circulating tumor
  • small cell lung cancer
  • cell free
  • circulating tumor cells
  • brain metastases
  • single molecule