Amplatzer Amulet Left Atrial Appendage Occluder Versus Watchman Device for Stroke Prophylaxis (Amulet IDE): A Randomized, Controlled Trial.
Dhanunjaya R LakkireddyDavid ThalerChristopher R EllisVijendra SwarupLars SondergaardJohn CarrollMichael R GoldJames HermillerHans-Christoph DienerBoris SchmidtLee MacDonaldMoussa MansourBrijeshwar MainiLaura O'BrienStephan WindeckerPublished in: Circulation (2021)
The Amulet occluder was noninferior for safety and effectiveness of stroke prevention for nonvalvular atrial fibrillation compared with the Watchman device and superior for LAA occlusion. Procedure-related complications were higher with the Amulet occluder and decreased with operator experience. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02879448.
Keyphrases
- left atrial appendage
- atrial fibrillation
- catheter ablation
- oral anticoagulants
- left atrial
- direct oral anticoagulants
- heart failure
- randomized controlled trial
- systematic review
- percutaneous coronary intervention
- risk factors
- minimally invasive
- venous thromboembolism
- acute coronary syndrome
- coronary artery disease
- blood brain barrier