Unraveling the Role of Histone Variant CENP-A and Chaperone HJURP Expression in Thymic Epithelial Neoplasms.

Georgia LevidouKonstantinos PalamarisAlexandros G SykarasGeorgios AndreadakisChristos Masaoutis Irene TheochariPenelope KorkolopoulouDimitra RontogianniStamatios Theocharis

Published in: International journal of molecular sciences (2022)

Our results suggest a significant interaction between CENP-A and HJURP in TETs. Moreover, we confirmed the presence of a cytoplasmic CENP-A immunolocalization, suggesting also a possible favorable prognostic value of this specific immunostaining pattern.

Keyphrases

poor prognosis
dna methylation
heat shock
long non coding rna
oxidative stress