USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells.
Yuning LiaoZhenlong ShaoYuan LiuXiaohong XiaYuanfei DengCuifu YuWenshuang SunWeiyao KongXiaoyue HeFang LiuZhiqiang GuoGuoxing ChenDaolin TangHuoye GanJinbao LiuHongbiao HuangPublished in: Journal of experimental & clinical cancer research : CR (2021)
These findings reveal a previously unrecognized role for the activation of USP1-RPS16 pathway in driving HCC, which may be further developed as a novel strategy for cancer treatment.