Probing transcription factor combinatorics in different promoter classes and in enhancers.
Jimmy VandelOcéane CassanSophie LèbreCharles-Henri LecellierLaurent BréhélinPublished in: BMC genomics (2019)
TFcoop appears as an accurate approach for studying TF combinations. Its use on ENCODE and FANTOM data allowed us to discover important properties of human TF combinations in different promoter classes and in enhancers. The R code for learning a TFcoop model and for reproducing the main experiments described in the paper is available in an R Markdown file at address https://gite.lirmm.fr/brehelin/TFcoop .