Conservative versus Interventional Treatment for Spontaneous Pneumothorax.
Simon G A BrownEmma L BallKyle PerrinStephen E AshaIrene BraithwaiteDiana Egerton-WarburtonPeter G JonesGerben KeijzersFrances B KinnearBen C H KwanK V LamY C Gary LeeMike NowitzCatherine A ReadGraham SimpsonJulian A SmithQuentin A SummersMark WeatherallRichard Beasleynull nullPublished in: The New England journal of medicine (2020)
Although the primary outcome was not statistically robust to conservative assumptions about missing data, the trial provides modest evidence that conservative management of primary spontaneous pneumothorax was noninferior to interventional management, with a lower risk of serious adverse events. (Funded by the Emergency Medicine Foundation and others; PSP Australian New Zealand Clinical Trials Registry number, ACTRN12611000184976.).