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Squamous cell carcinoma of the ovary arising from a mature cystic teratoma associated with hypercalcaemia.

Annalisa MontebelloNicoletta ManiscalcoMartina GrechAndrew CuschieriKristel Marie Von Brockdorff
Published in: British journal of hospital medicine (London, England : 2005) (2024)
We present a rare case of a 40-year-old nulliparous lady, with no past medical or surgical history, who was diagnosed with metastatic squamous cell carcinoma of the right ovary that originated from a mature cystic ovarian teratoma. Our patient underwent debulking total abdominal hysterectomy, bilateral salpingo-oophorectomy and partial omentectomy followed by postoperative carboplatin and paclitaxel chemotherapy. Rapid disease progression ensued, complicated by severe parathyroid hormone-related protein-induced hypercalcaemia resistant to medical therapy. The patient was treated in a palliative manner and died five months after her diagnosis.
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