UVB-Induced Secretion of IL-1 β Promotes Melanogenesis by Upregulating TYR/TRP-1 Expression In Vitro.

Chun-Yan YangYanni GuoWen-Juan WuMao-Qiang ManYing TuLi He

Published in: BioMed research international (2022)

can also stimulate the expression of COX-2 and SCF in HaCaT cells, which in turn increase melanin synthesis in melanocytes. These results suggest that anti-inflammatory approaches could possibly mitigate UVB-induced hyperpigmentation.

Keyphrases

poor prognosis
high glucose
diabetic rats
anti inflammatory
induced apoptosis
drug induced
binding protein
oxidative stress
cell cycle arrest
long non coding rna
endoplasmic reticulum stress
signaling pathway