Metabolomic fingerprint of severe obesity is dynamically affected by bariatric surgery in a procedure-dependent manner.
Ewa GralkaClaudio LuchinatLeonardo TenoriBarbara ErnstMartin ThurnheerBernd SchultesPublished in: The American journal of clinical nutrition (2015)
Our data indicate that bariatric surgery, irrespective of the specific kind of procedure used, reverses most of the metabolic alterations associated with obesity and suggest profound changes in gut microbiome-host interactions after the surgery. This trial was registered at clinicaltrials.gov as NCT02480322.
Keyphrases
- bariatric surgery
- weight loss
- minimally invasive
- obese patients
- insulin resistance
- metabolic syndrome
- type diabetes
- weight gain
- high fat diet induced
- study protocol
- clinical trial
- coronary artery bypass
- intellectual disability
- randomized controlled trial
- early onset
- body mass index
- physical activity
- atrial fibrillation
- drug induced
- open label
- percutaneous coronary intervention
- surgical site infection
- quality control