Characteristics and Outcomes of Clinical Trials on Gene Therapy in Noncongenital Cardiovascular Diseases: Cross-sectional Study of Three Clinical Trial Registries.
Witold PinczakSylwia TrzcińskaKamiński MikołajPublished in: JMIR formative research (2022)
Among noncongenital cardiovascular diseases, GTs are mostly investigated in peripheral artery disease and coronary artery disease. Many clinical trials on GT use in noncongenital cardiovascular diseases did not disclose their results. Regardless of the trial phase, less than half of published studies on GT in noncongenital cardiovascular diseases showed promising results.
Keyphrases
- clinical trial
- cardiovascular disease
- phase ii
- gene therapy
- coronary artery disease
- phase iii
- peripheral artery disease
- study protocol
- cardiovascular events
- open label
- cardiovascular risk factors
- double blind
- type diabetes
- randomized controlled trial
- systematic review
- percutaneous coronary intervention
- skeletal muscle
- mass spectrometry
- left ventricular