Unraveling the therapeutic efficacy of resveratrol in Alzheimer's disease: an umbrella review of systematic evidence.
Ali AzargoonjahromiFatemeh AbutalebianPublished in: Nutrition & metabolism (2024)
RV exhibits promising potential for benefiting individuals with AD through various mechanisms. It has been observed to enhance cognitive function, reduce Aβ accumulation, provide neuroprotection, protect the BBB, support mitochondrial function, facilitate synaptic plasticity, stabilize tau proteins, mitigate oxidative stress, and reduce neuroinflammation commonly associated with AD.
Keyphrases
- oxidative stress
- mycobacterium tuberculosis
- cerebral ischemia
- blood brain barrier
- traumatic brain injury
- brain injury
- cognitive decline
- dna damage
- cognitive impairment
- cerebrospinal fluid
- lps induced
- human health
- randomized controlled trial
- subarachnoid hemorrhage
- induced apoptosis
- diabetic rats
- risk assessment
- inflammatory response
- signaling pathway