Treatment-Resistant Depression in Real-World Clinical Practice: A Systematic Literature Review of Data from 2012 to 2022.
Albino J Oliveira-MaiaAnia BobrowskaEric ConstantTetsuro ItoYerkebulan KambarovHannah LuedkeSiobhán Mulhern-HaugheyChristian von HoltPublished in: Advances in therapy (2023)
There is a lack of clinical consensus regarding the definition, assessment and monitoring of TRD in real-world practice. Nevertheless, TRD carries a high burden of illness and there is an unmet need for faster and more effective treatments. To better understand the personal burden of affected patients, future studies would benefit from standardisation of severity assessment and measures of treatment effectiveness, as well as greater consideration of health-related quality of life.
Keyphrases
- clinical practice
- end stage renal disease
- ejection fraction
- newly diagnosed
- randomized controlled trial
- primary care
- prognostic factors
- depressive symptoms
- electronic health record
- risk factors
- big data
- physical activity
- patient reported outcomes
- deep learning
- quality improvement
- data analysis
- artificial intelligence