A single mutation in the ACTR8 gene associated with lineage-specific expression in primates.

Se-Hee ChoeSang-Je ParkHyeon-Mu ChoHye-Ri ParkJa-Rang LeeYoung-Hyun KimJae-Won Huh

Published in: BMC evolutionary biology (2020)

The single G duplication in the TE sequence is the source of TE exonization and AS, and this mutation may suffer a different fate of ACTR8 gene expression during primate evolution.

Keyphrases

gene expression
poor prognosis
dna methylation
genome wide
copy number
single cell
cell fate