Functional inhibition of F11 receptor (F11R/junctional adhesion molecule-A/JAM-A) activity by a F11R-derived peptide in breast cancer and its microenvironment.

Radoslaw BednarekAnna SelmiDagmara WojkowskaKamil KarolczakMarcin PopielarskiMarta StasiakMoro O SalifuAnna BabinskaMaria Swiatkowska

Published in: Breast cancer research and treatment (2019)

F11R/JAM-A protein can be considered as a novel target in the treatment of breast cancer metastasis. In vivo and clinical studies are needed to further investigate the effectiveness of F11R/JAM-A-derived peptide as a possible anti-metastatic drug.

Keyphrases

randomized controlled trial
squamous cell carcinoma
small cell lung cancer
systematic review
binding protein
emergency department
protein protein
amino acid
escherichia coli
pseudomonas aeruginosa
staphylococcus aureus
replacement therapy
young adults