Antihypertensive drug effects on long-term blood pressure: an individual-level data meta-analysis of randomised clinical trials.

Dexter Canoy Emma Copland Milad Nazarzadeh Rema RamakrishnanAna-Catarina Pinho-GomesAbdul SalamJamie P DwyerFarshad FarzadfarJohan Sundström Mark WoodwardBarry R DavisKazem Rahiminull nullnull null

Published in: Heart (British Cardiac Society) (2022)

These findings suggest that BP-lowering pharmacotherapy is effective in lowering BP, up to 4 years on average, in people with different characteristics. Appropriate treatment strategies are needed to sustain substantive long-term BP reductions.

Keyphrases

blood pressure
clinical trial
systematic review
hypertensive patients
open label
heart rate
meta analyses
electronic health record
randomized controlled trial
phase ii
big data
emergency department
phase iii
case control
insulin resistance
weight loss