Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory.
Ji Won HanPauline MaillardDanielle HarveyEvan FletcherOliver MartinezDavid K JohnsonJohn M OlichneySarah T FariasSylvia VilleneuveWilliam JagustDan MungasCharles DeCarliPublished in: Neurology (2020)
Vascular brain injury and neurodegeneration are associated with baseline cognitive performance and the rate of longitudinal change independent of amyloid status among community-dwelling, ethnicity diverse cognitively normal individuals, supporting the role of vascular diseases as risk factors for later-life dementia.