Ten-eleven translocation protein 1 modulates medulloblastoma progression.

Hyerim KimYunhee KangYujing LiLi ChenLi LinNicholas D JohnsonDan ZhuM Hope RobinsonLeon McSwainBenjamin G BarwickXianrui YuanXinbin LiaoJie ZhaoZhiping ZhangQiang ShuJianjun ChenEmily G AllenAnna M KenneyRobert C CastellinoErwin G Van MeirKaren N ConneelyPaula M VertinoPeng JinJian Li

Published in: Genome biology (2021)

These results together suggest a potential key role of 5hmC and indicate an oncogenic nature for TET1 in MB tumorigenesis, suggesting it as a potential therapeutic target for MBs.

Keyphrases

human health
protein protein
binding protein