Influence of formulation and route of administration on ketamine's safety and tolerability: systematic review.

Paul GlueBruce RussellNatalie J Medlicott

Published in: European journal of clinical pharmacology (2020)

Ketamine formulations that maximize first pass metabolism and delay Tmax will be better tolerated and safer than formulations which lack those characteristics.

Keyphrases

systematic review
pain management
meta analyses
open label
drug delivery
randomized controlled trial