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Pantoprazole in ICU patients at risk for gastrointestinal bleeding-1-year mortality in the SUP-ICU trial.

Søren MarkerMette KragAnders PernerJørn WetterslevTheis LangeMatt P WiseMark BorthwickStepani BendelFrederik KeusAnne Berit GuttormsenJoerg C SchefoldBodil S RasmussenThomas ElkmannMorten BestleBjørn ArenkielJon Henrik LaakeMaj K KamperMaarit LångMalgorzata B Pawlowicz-DworzanskaSari KarlssonJanne Henrik LiisananttiNilanjan DeyHeidi KnudsenAnders GranholmMorten Hylander Möllernull null
Published in: Acta anaesthesiologica Scandinavica (2019)
We did not observe a difference in 1-year mortality among acutely admitted adult ICU patients with risk factors for gastrointestinal bleeding allocated to stress ulcer prophylaxis with pantoprazole or placebo during the ICU stay. (The SUP-ICU trial was funded by Innovation Fund Denmark and others; ClinicalTrials.gov number, NCT02467621).
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