Fatty acids and recurrence of major depressive disorder: combined analysis of two Dutch clinical cohorts.
Carisha S ThesingA LokY MilaneschiJ AssiesC L H BocktingC A FigueroaE J GiltayB W J H PenninxH G RuhéA H ScheneM BotR J T MockingPublished in: Acta psychiatrica Scandinavica (2019)
In remitted MDD patients, circulating PUFAs were not associated with prospective risk of MDD recurrence. Consequently, circulating PUFAs are unlikely to reflect a vulnerability marker for recurrence, so correcting n-3 PUFA 'deficits' through supplementation does not seem a promising option to prevent MDD recurrence.