Human memory CD4+ T cell response to the major dog allergen Can f 5, prostatic kallikrein.
A KailaanmäkiT KinnunenA RönkäMarja Rytkönen-NissinenJ LidholmL MattssonJ RandellT VirtanenPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
Can f 5-specific memory CD4+ T cell responses differ considerably between subjects with and without allergy, as assessed by both in vitro and ex vivo approaches. Peptides containing the dominant T cell epitopes of Can f 5 can be employed for developing peptide-based immunotherapy for dog allergy.