Acute myeloid leukemia with RAM immunophenotype: A new underdiagnosed entity.

Smeeta GajendraShilpa AnupurbaRitu Gupta Saumyaranjan Mallick Devasis PandaDeepshi ThakralSanjeev Kumar Gupta Sameer BakhshiRachna SethSandeep RaiVijay K PrajapatiSaroj Singh

Published in: International journal of laboratory hematology (2023)

AML with RAM immunophenotype, a distinct form of pediatric AML with a poor prognosis, may pose a diagnostic challenge if presented as a soft tissue mass. A comprehensive immunophenotypic evaluation, including stem cell and myeloid markers, is critical for an accurate diagnosis of myeloid sarcoma with the RAM-immunophenotype. Our data demonstrated weak CD13 expression as an additional immunophenotypic finding.

Keyphrases

acute myeloid leukemia
poor prognosis
stem cells
long non coding rna
soft tissue
allogeneic hematopoietic stem cell transplantation
electronic health record
big data
high resolution
dendritic cells
acute lymphoblastic leukemia
nk cells
data analysis
immune response