The Effect of Gaussian Noise on Maximum Likelihood Fitting of Gompertz and Weibull Mortality Models with Yeast Lifespan Data.

Our study shows that Gaussian white noise can influence the fitting of an aging model for yeast replicative lifespans. Given that yeast replicative lifespans are hard to measure and are often pooled from different experiments, our study highlights that interpreting model fitting results should take experimental procedure variation into account, and the best fitting model may not necessarily offer more biological insights.