Does the compromised sleep and circadian disruption of night and shiftworkers make them highly vulnerable to 2019 coronavirus disease (COVID-19)?
Flavia Rodrigues da SilvaRenato de Carvalho GuerreiroHenrique de Araújo AndradeEduardo StielerAndressa SilvaMarco Tulio de MelloPublished in: Chronobiology international (2020)
ACE2: Angiotensin-converting enzyme 2; APC: Antigen.-presenting .cells; CCL: Chemokine (C-C motif) ligand; CD+: .Adhesion molecule expression; COVID-19: 2019 coronavirus disease; DCs: Dendritic cells; GH: Growth hormone; HPA: Hypothalamic-pituitary-adrenal; HSF: Heat shock factor; HSP70: Heat shock protein 70; HSP90: Heat shock protein 90; IL: Interleukin; INFγ: Interferon-gamma; LT/LB: T/B lymphocytes; MHC: Major histocompatibility complex; NK: Natural .killer; RAAS: renin-angiotensin-aldosterone system; SARS: .Severe acute respiratory syndrome; SCN: Suprachiasmatic nucleus;SD: Sleep deprivation; SNS: Sympathetic nervous system; Th1/Th2: T helper lymphocytes 1/2; TLR2/TLR4: Toll-like receptor 2/4; TNF-α: Tumor .necrosis .factor alpha; VEGF: Vascular endothelial growth factor.
Keyphrases
- coronavirus disease
- heat shock protein
- angiotensin converting enzyme
- toll like receptor
- heat shock
- growth hormone
- vascular endothelial growth factor
- dendritic cells
- angiotensin ii
- immune response
- sleep quality
- nk cells
- nuclear factor
- inflammatory response
- regulatory t cells
- rheumatoid arthritis
- peripheral blood
- induced apoptosis
- endothelial cells
- respiratory syndrome coronavirus
- physical activity
- case report
- poor prognosis
- cell cycle arrest
- biofilm formation
- heat stress
- endoplasmic reticulum stress
- depressive symptoms
- pseudomonas aeruginosa
- staphylococcus aureus
- liver injury
- cell death
- escherichia coli
- sars cov
- candida albicans
- liver fibrosis
- respiratory tract