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Pursuit of Noncovalent Interactions for Strategic Site-Selective Catalysis.

F Dean TosteMatthew S SigmanScott J Miller
Published in: Accounts of chemical research (2018)
Selective reactions on structures of high complexity can move beyond the mind's eye and proof-of-principle. Enhanced understanding of noncovalent interactions and their interdependence, revealed through analysis of multiple parameters, should accelerate the discovery of efficient reactions in highly complex molecular environments.
Keyphrases
  • small molecule
  • high resolution
  • single cell
  • single molecule