Association between endogenous plasma beta-hydroxy-beta-methylbutyrate levels and frailty in community-dwelling older people.

Begoña Molina-BaenaJose Antonio CarniceroSuzette L PereiraFrancisco José García-GarcíaAngela Santos-FandilaRicardo Rueda CabreraLeocadio Rodríguez-Mañas

Published in: Journal of cachexia, sarcopenia and muscle (2023)

There is an inverse association between HMB levels and frailty status. These findings support the design of targeted clinical trials to evaluate the effect of HMB supplementation in older frail people with low HMB levels.

Keyphrases

community dwelling
clinical trial
physical activity
randomized controlled trial
study protocol