Efficacy of Varenicline in the Treatment of Alcohol Dependence: An Updated Meta-Analysis and Meta-Regression.

Wiraphol PhimarnRotjanawat SakhancordPeerasaran PaitoonKritsanee Saramunee Bunleu Sungthong

Published in: International journal of environmental research and public health (2023)

Our results indicated that AD patients treated with varenicline showed improvement in percentage of very heavy drinking days, percentage of abstinent days, drinks per day, drinks per drinking day, and craving. However, well-designed RCTs with a large sample size and long duration on varenicline treatment in AD remain warranted to confirm our findings.

Keyphrases

systematic review
smoking cessation
replacement therapy
alcohol consumption
randomized controlled trial
combination therapy