Evaluation of Murine Host Sex as a Biological Variable in Transplanted Human Intestinal Organoid Development.
Eoin P McNeillVikas S GuptaDavid J SequeiraNoah F ShroyerAllison L SpeerPublished in: Digestive diseases and sciences (2022)
While male host sex was associated with larger tHIO lumen size and mucosal maturation, tHIOs from both groups had similar engraftment, growth, and epithelial and mesenchymal cytodifferentiation.