Maternal adiposity is associated with inflammatory gene expression in leukocytes at term human pregnancy: A pilot study.
Karla MacDonald-RamosRodrigo Vega-SanchezPublished in: Molecular genetics & genomic medicine (2020)
Our findings suggest that during term pregnancy, increased maternal adiposity may enhance the priming of peripheral leukocytes, while in choriodecidua it may alter leukocyte recruitment and proinflammatory activity. Maternal adiposity must be considered an important variable in further studies that analyze inflammation-related gene expression in pregnant women.
Keyphrases
- pregnancy outcomes
- gene expression
- pregnant women
- birth weight
- gestational age
- insulin resistance
- weight gain
- preterm birth
- peripheral blood
- dna methylation
- oxidative stress
- preterm infants
- endothelial cells
- type diabetes
- adipose tissue
- metabolic syndrome
- body mass index
- skeletal muscle
- induced pluripotent stem cells
- weight loss
- physical activity
- pluripotent stem cells
- case control