Clinical and Pharmacokinetic Outcomes of Peak-Trough-Based Versus Trough-Based Vancomycin Therapeutic Drug Monitoring Approaches: A Pragmatic Randomized Controlled Trial.

Fatima Khalifa Al-SulaitiAhmed Mohamed NaderMohamed Omar SaadAdila ShaukatRakesh ParakadavathuAhmed ElzubairDaoud Al-BadriyehHazem ElewaAhmed Awaisu

Published in: European journal of drug metabolism and pharmacokinetics (2020)

Maintenance of target vancomycin exposures and implementation of peak-trough-based vancomycin TDM may improve vancomycin-associated cure rates. Larger scale RCTs are warranted to confirm these findings.

Keyphrases

methicillin resistant staphylococcus aureus
randomized controlled trial
study protocol
primary care
healthcare
air pollution
type diabetes
clinical trial
metabolic syndrome
skeletal muscle