Evaluation of acquired antithrombin deficiency in paediatric patients supported on extracorporeal membrane oxygenation.
David E ProcacciniJennifer RoemDerek K NgThomas E RappoldDawoon JungJogarao V S GobburuMelania M BembeaPublished in: British journal of clinical pharmacology (2023)
There was a high prevalence of AT deficiency in paediatric ECMO patients. An AT replacement protocol based on evaluating heparin resistance is associated with fewer AT administrations, with similar circuit and patient outcomes. Further data are needed to identify optimal dosing strategies.
Keyphrases
- extracorporeal membrane oxygenation
- end stage renal disease
- ejection fraction
- acute respiratory distress syndrome
- newly diagnosed
- chronic kidney disease
- emergency department
- intensive care unit
- randomized controlled trial
- peritoneal dialysis
- prognostic factors
- machine learning
- artificial intelligence
- big data
- smoking cessation