LAMTOR5 expression level is a biomarker for colorectal cancer and lncRNA LAMTOR5-AS1 predicting miRNA sponging effect.

Najmeh Riahi ZanianiAndisheh OroujalianAli ValipourMaryam Peymani

Published in: Molecular biology reports (2021)

LAMTOR5 gene can be considered as prognostic biomarker for CRC. LAMTOR5-AS5 which is a nearby lncRNA of this gene could play a regulatory impact through its sponging effect on hsa-miR-let-7b-3p and hsa-miR-20a-5p which both have shown a significant impact on overall survival rate in CRC patients in high expression levels.

Keyphrases

long non coding rna
poor prognosis
end stage renal disease
long noncoding rna
cell proliferation
newly diagnosed
ejection fraction
copy number
genome wide
chronic kidney disease
binding protein
transcription factor
peritoneal dialysis
patient reported