Vasorelaxant properties of Vernonia amygdalina ethanol extract and its possible mechanism.

Yung Sing Ch'ngYean Chun LohChu Shan TanMariam AhmadMohd Zaini AsmawiWan Maznah Wan OmarMun Fei Yam

Published in: Pharmaceutical biology (2018)

The vasorelaxation effect of VAE involves upregulation of NO/cGMP and PGI2 signalling pathways, and modulation of calcium/potassium channels, and muscarinic and β2-adrenergic receptor levels.

Keyphrases

nitric oxide
poor prognosis
oxidative stress
cell proliferation
protein kinase
signaling pathway
anti inflammatory