Infiltration of subcutaneous adipose layer into the dermal layer with aging.
Tomonobu EzureSatoshi AmanoKyoichi MatsuzakiPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2022)
Our findings indicate that subcutaneous fat infiltrates into the dermal layer of aged skin. Our 3D analysis approach is advantageous to understand changes of complex internal skin structures with aging.