Dexamethasone-Free Antiemetic Prophylaxis for Highly Emetogenic Chemotherapy: A Double-Blind, Phase III Randomized Controlled Trial (CINV POD study).

Venkatraman RadhakrishnanKritthivasan VenkatakrishnanJayachandran Perumal Kalaiyarasi Gangothri SelvarajanNizamudin MahaboobashaPaulson Vijaykumar VictorMalarvizhi AnbazhaganDeyva Manohari SivanandamSwaminathan Rajaram

Published in: JCO global oncology (2024)

This study shows that a DEX-free OPF regimen is efficacious and should be considered a standard option for acute and delayed CINV prophylaxis for HEC.

Keyphrases

randomized controlled trial
chemotherapy induced
phase iii
clinical trial
open label
low dose
liver failure
high dose
intensive care unit
hepatitis b virus
locally advanced
rectal cancer