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Tofacitinib in Pediatric Ulcerative Colitis: A Retrospective Multicenter Experience.

Oren LedderMichael DolingerMarla C DubinskyRonen SteinSrisindu VellankiRachel BuckukAyesha FatimaDavid L SuskindJarrad ScarlettDennis RöserDror S ShouvalGabriele MeyerZarela Molle RiosGemma Pujol-MuncunillAnna LozanoKaija-Leena KolhoPejman RohaniSéamus HusseyTim de MejjTravis AyersVictor Manuel Navas-LópezDan TurnerChristos Tzivinikos
Published in: Inflammatory bowel diseases (2024)
In this largest real-life pediatric cohort to date, tofacitinib was effective in at least 16% of patients with highly refractory UC by week 8. Adverse events were minor and largely consistent with adult data.
Keyphrases
  • ulcerative colitis
  • rheumatoid arthritis
  • childhood cancer
  • electronic health record
  • big data
  • clinical trial
  • young adults
  • double blind
  • randomized controlled trial
  • deep learning
  • data analysis
  • placebo controlled