Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres.

Hyeong-Cheol OhJin-Kyoung ShimJunseong ParkJi-Hyun LeeRan Joo ChoiNam Hee KimHyun Sil KimJu Hyung MoonEui Hyun KimJong Hee ChangJong In YookSeok-Gu Kang

Published in: Journal of cancer research and clinical oncology (2020)

The combination of niclosamide and temozolomide effectively decreased the stemness and invasive properties of GBM TSs, suggesting that this regimen may be therapeutically effective in treating patients with GBM.

Keyphrases

endothelial cells
newly diagnosed
stem cells
epithelial mesenchymal transition
induced pluripotent stem cells
pluripotent stem cells