Indoxyl Sulfate Aggravates Podocyte Damage through the TGF-β1/Smad/ROS Signalling Pathway.
Miao JiaLihua LinKang XunDamei LiWeijiang WuShaobo SunHong QiuDonghua Jin
Published in: Kidney & blood pressure research (2024)
This study suggests that IS may modulate the expression of nephrin, synaptopodin, CD2AP, and SRGAP2a by regulating the ROS and TGF-β1/Smad signalling pathways, providing new theoretical support for the treatment of diabetic nephropathy.