Impact on antimicrobial consumption of procalcitonin-guided antibiotic therapy for pneumonia/pneumonitis associated with aspiration in comatose mechanically ventilated patients: a multicenter, randomized controlled study.
Guylaine LabroFrançois AptelMarc PuyraveauJonathan PaillotSébastien Pili FlouryHamid MerdjiJulie HelmsGaël PitonFiona EcarnotKhaldoun KuteifanJean-Pierre QuenotGilles Capelliernull nullPublished in: Annals of intensive care (2021)
The use of PCT values to guide therapy, in comparison to the use of clinical, biological (apart from PCT) and radiological criteria, does not modify exposure to antibiotics in patients intubated for coma. Trial registration Clinicaltrials.gov Identifier NCT02862314.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- clinical trial
- staphylococcus aureus
- double blind
- stem cells
- patient reported outcomes
- systemic sclerosis
- acute respiratory distress syndrome
- placebo controlled
- rheumatoid arthritis
- cross sectional
- open label
- patient reported
- bone marrow