Evaluation of changes in cardiac longitudinal strain rate in patients with systemic sclerosis undergoing iloprost treatment: an observational study.
Ivan IsaiaPaola AparoFederica CastellettiMatteo RegoloMaria Letizia AprilePaolo FiorenzaGianluca SambataroLorenzo Salvatore MalatinoMichele ColaciPublished in: Rheumatology (Oxford, England) (2024)
Iloprost administration improved GLS, suggesting that the increase of myocardial perfusion allowed, at least in part, a correction of left ventricular systolic dysfunction. Further studies are needed to confirm these findings, further exploring the mid/long-term effects of Iloprost on myocardial contraction.
Keyphrases
- left ventricular
- systemic sclerosis
- interstitial lung disease
- hypertrophic cardiomyopathy
- heart failure
- cardiac resynchronization therapy
- acute myocardial infarction
- aortic stenosis
- left atrial
- mitral valve
- oxidative stress
- blood pressure
- cross sectional
- ejection fraction
- combination therapy
- case control
- transcatheter aortic valve replacement
- percutaneous coronary intervention
- smoking cessation