Guideline-defined futility or patient-reported outcomes to assess treatment success after TAVI: what to use? Results from a prospective cohort study with long-term follow-up.
Martijn Stefan van MourikJeroen VendrikMohammad AbdelghaniFloortje van KesterenJose P S HenriquesAntoine H G DriessenJoanna J WykrzykowskaRobbert J de WinterJan J PiekJan G TijssenKarel T KochJan BaanM Marije VisPublished in: Open heart (2018)
Lower albumin and non-transfemoral access route were predictors for guideline-defined TAVI futility, defined as mortality within 1 year or no objective symptomatic improvement in New York Heart Association class. Futility according to this definition occurred frequently in this study, contrasting with much more positive PROMs. The majority of patients would undergo a TAVI again, underlining the patients' experienced value of TAVI and putting the definition of TAVI futility further on debate. In the near future, less-strict criteria for TAVI futility, that is, using a shorter warranted life expectancy and incorporating patients' perceived outcomes, should be used.
Keyphrases
- patient reported outcomes
- transcatheter aortic valve implantation
- transcatheter aortic valve replacement
- ejection fraction
- end stage renal disease
- aortic valve
- aortic stenosis
- chronic kidney disease
- heart failure
- mental health
- physical activity
- risk factors
- insulin resistance
- coronary artery disease
- cardiovascular events
- social support
- combination therapy
- patient reported