Pre-HAART CD4+ T-lymphocytes as biomarkers of post-HAART immune recovery in HIV-infected children with or without TB co-infection.

Vivek GopalakrishnanEliezer BoseUsha NairYuwei ChengMusie Ghebremichael

Published in: BMC infectious diseases (2020)

Pre-HAART CD4+ T-lymphocyte count and percentage are stronger predictors of immune recovery in TB-negative pediatric patients, suggesting that TB co-infection complicates the treatment of HIV in this cohort. These findings suggest that the detection and treatment of TB is essential for the effectiveness of HAART in HIV-infected pediatric patients.

Keyphrases

hiv infected
antiretroviral therapy
hiv infected patients
mycobacterium tuberculosis
human immunodeficiency virus
hiv aids
hiv positive
randomized controlled trial
systematic review
peripheral blood
young adults
combination therapy
replacement therapy
hiv testing
smoking cessation