The lncRNA NEAT1 Inhibits miRNA-216b and Promotes Colorectal Cancer Progression by Indirectly Activating YY1.

Yuping ZhuXuanying WangLinfeng ZhengDechuan LiZhuo LiuLi Song Teng

Published in: Journal of oncology (2022)

Our results indicated that NEAT1 acted as an oncogene in CRC and promoted the progression of CRC by directly sponging miR-216 b expression to activate the expression of YY1. The NEAT1/miR-216b/YY1 axis may be a novel therapeutic target for CRC.

Keyphrases

poor prognosis
long non coding rna
binding protein
signaling pathway