Depletion of ATP and glucose in advanced human atherosclerotic plaques.

Matias EkstrandEmma WidellAnna HammarLevent M AkyürekMartin JohanssonBjörn FagerbergGöran BergströmMalin C LevinPer FogelstrandJan BorénMax Levin

Published in: PloS one (2017)

Our study demonstrates severe ATP depletion and glucose deficiency in the perinecrotic zone of human advanced atherosclerotic plaques. ATP depletion may impair healing of plaques and promote disease progression.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
blood glucose
type diabetes
early onset
insulin resistance
smoking cessation