HYDIN loss-of-function inhibits GATA4 expression and enhances atrial septal defect risk.

Yu CaoJunying GuoJinping ZhangLi LiHui WangWenjun RenLihong Jiang

Published in: Mechanisms of development (2020)

HYDIN loss-of-function inhibits GATA4 expression and enhances ASD risk. We also establish the regulation of a key transcription factor in heart development by a ciliary protein.

Keyphrases

transcription factor
poor prognosis
binding protein
atrial fibrillation
autism spectrum disorder
attention deficit hyperactivity disorder
dna binding
long non coding rna
small molecule
intellectual disability
protein protein
mitral valve