Induced neuroprotection by remote ischemic perconditioning as a new paradigm in ischemic stroke at the acute phase, a systematic review.
Francisco F PurroyCristina GarcíaGerard MauriCristina PereiraCoral TorresDaniel Vazquez-JustesMikel Vicente-PascualAna VenaGloria ArquePublished in: BMC neurology (2020)
This review summarizes the completed and ongoing clinical trials on RIPerC in IS patients, where RIPerC has been used alone or in combination with recanalization therapies. Ongoing clinical trials will provide new information on the best RIPerC intervention strategy and potentially improve the functional outcome of IS patients; definition of new RIPerC strategies would ideally aim at enhancing tissue preservation, promoting neurological recovery, and stratify patients to improve treatment feasibility.
Keyphrases
- end stage renal disease
- clinical trial
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- randomized controlled trial
- peritoneal dialysis
- patient reported outcomes
- endothelial cells
- brain injury
- open label
- study protocol
- high glucose
- phase ii
- double blind
- smoking cessation
- drug induced
- phase iii