Effects of Regulation on Carbapenem Prescription in a Large Teaching Hospital in China: An Interrupted Time Series Analysis, 2016-2018.

Lewei XieYaling DuXuemei WangXinping ZhangChenxi LiuJunjie LiuXi PengXinhong Guo

Published in: Infection and drug resistance (2021)

The intervention effectively reduced the IAC of carbapenems and imipenem, carbapenem consumption and the ALoS in the ICU, and the IAC of meropenem in all departments. The effects of the intervention were significant in the ICU, which indicated an urgent need for stronger regulations focusing on critical departments in the future.

Keyphrases

gram negative
randomized controlled trial
acinetobacter baumannii
klebsiella pneumoniae
intensive care unit
multidrug resistant
mechanical ventilation
drug resistant
escherichia coli
acute respiratory distress syndrome